Association of EPHX2 R287Q Polymorphism with Diabetic Nephropathy in Chinese Type 2 Diabetic Patients

Table 1

Characteristics of DM patients with DN (cases) and without DN (controls).

	DM patients with DN ()^a	DM patients without DN ()^a
Age (years)	63 (54, 71)	61 (54, 68)	0.001
Sex, male (%)	63.55 (258/406)	58.41 (271/464)	0.121
BMI (kg/m^2)	25.80 (23.89, 28.36)	25.36 (23.20, 27.68)	0.006
Duration of diabetes (years)	15 (9, 21)	13 (10, 18)	0.097
History of hypertension (%)	78.82 (320/406)	49.35 (229/464)	<0.001
Smoking (%)	34.73 (141/406)	28.23 (131/464)	0.039
SBP (mmHg)	138 (125, 150)	127 (120, 140)	<0.001
DBP (mmHg)	80 (74, 84)	80 (70, 80)	0.048
A1C (%)	7.6 (6.5, 9.3)	7.9 (6.7,9.3)	0.148
Hcy (umol/L)	13.63 (11.03, 17.12)	11.48 (9.51, 13.42)	<0.001
TC (mmol/L)	4.25 (3.44, 5.06)	4.14 (3.53, 4.86)	0.36
HDL-C (mmol/L)	0.96 (0.78, 1.18)	1.02 (0.85, 1.24)	0.004
LDL-C (mmol/L)	2.39 (1.85, 2.98)	2.38 (1.94, 2.97)	0.535
TG (mmol/L)	1.71 (1.20, 2.56)	1.42 (0.99, 2.18)	<0.001

BMI: body mass index; DBP: diastolic blood pressure; Hcy: homocysteine; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol SBP: systolic blood pressure; TC: triglyceride. ^aData are shown as median (interquantile range) or %.