Ultrasonographic Characterization of the db/db Mouse: An Animal Model of Metabolic Abnormalities

Table 2

Ultrasonographic cardiac parameters in the two groups of mice.

	wt	db/db
LVmass (mg)	91 [13]	77 [17]
CO (ml/min)	13.49 [6.63]	7.01 [3.53]
SV (l)	38.88 [17.37]	22.82 [8.73]
FS (%)	14.80 [6.50]	9.24 [6.04]
EF (%)	53.50 [9.35]	44.24 [10.56]
E/A	1.37 [0.37]	2.00 [0.75]
gLS (%)	−14.39 [5.76]	−14.49 [4.36]
gLSR (1/s)	−4.54 [1.51]	−4.75 [3.35]
gRS (%)	39.74 [11.81]	32.22 [14.75]
gRSR (1/s)	9.39 [3.17]	7.88 [3.31]
gCS (%)	−23.63 [5.99]	−24.96 [5.61]
gCSR (1/s)	−8.18 [2.09]	−8.75 [2.75]

Data are presented as median [IQR]. versus wt. LVmass: left ventricular mass; CO: cardiac output; SV: stroke volume; FS: fractional shortening; EF: ejection fraction; E/A: E/A ratio; gLS/gLSR: global longitudinal strain/strain rate; gRS/gRSR: global radial strain/strain rate; gCS/gCSR: global circumferential strain/strain rate.