Journal of Diabetes Research / 2018 / Article / Tab 2

Research Article

Ultrasonographic Characterization of the db/db Mouse: An Animal Model of Metabolic Abnormalities

Table 2

Ultrasonographic cardiac parameters in the two groups of mice.

wtdb/db

LVmass (mg)91 [13]77 [17]
CO (ml/min)13.49 [6.63]7.01 [3.53]
SV (l)38.88 [17.37]22.82 [8.73]
FS (%)14.80 [6.50]9.24 [6.04]
EF (%)53.50 [9.35]44.24 [10.56]
E/A1.37 [0.37]2.00 [0.75]
gLS (%)−14.39 [5.76]−14.49 [4.36]
gLSR (1/s)−4.54 [1.51]−4.75 [3.35]
gRS (%)39.74 [11.81]32.22 [14.75]
gRSR (1/s)9.39 [3.17]7.88 [3.31]
gCS (%)−23.63 [5.99]−24.96 [5.61]
gCSR (1/s)−8.18 [2.09]−8.75 [2.75]

Data are presented as median [IQR]. versus wt. LVmass: left ventricular mass; CO: cardiac output; SV: stroke volume; FS: fractional shortening; EF: ejection fraction; E/A: E/A ratio; gLS/gLSR: global longitudinal strain/strain rate; gRS/gRSR: global radial strain/strain rate; gCS/gCSR: global circumferential strain/strain rate.