Research Article
Impact of Metabolic Syndrome Factors on Testosterone and SHBG in Type 2 Diabetes Mellitus and Metabolic Syndrome
Table 1
Characterization of subjects included in the study.
| | Normal () | Metabolic syndrome () | Type 2 DM without metabolic syndrome () | Type 2 DM with metabolic syndrome () | ANOVA value |
| | Age (years) | 38 ± 7.7 | 44 ± 8.5 | 47 ± 9.7 | 51 ± 5.7 | 0.001 | | BMI | 22.6 ± 2.3 | 30.2 ± 2.9 | 25.3 ± 2.5 | 28.1 ± 2.4 | 1.4 × 10−21 | | Waist circumference | 85 ± 5.8 | 104 ± 6.7 | 91 ± 6.4 | 102 ± 5.4 | 3.1 × 10−25 | | Systolic blood pressure | 117 ± 9 | 136 ± 14 | 119 ± 15 | 136 ± 15 | 5.9 × 10−9 | | Diastolic blood Pressure | 76 ± 7 | 90 ± 10 | 77 ± 12 | 89 ± 12 | 2.2 × 10−8 | | Triglyceride (mg/dl) | 139 ± 51 | 199 ± 74 | 211 ± 81 | 233 ± 81 | 1.8 × 10−5 | | HDL-c (mg/dl) | 44 ± 8.6 | 42 ± 6.0 | 40 ± 5.7 | 40 ± 5.1 | 0.039847 | | FBG (mmol/l) | 5.1 ± 0.4 | 5.5 ± 0.6 | 10.0 ± 3.7 | 10.7 ± 3.1 | 6.2 × 10−19 | | Insulin (pmol/l) | 50 ± 21 | 116 ± 35 | 72 ± 30 | 88 ± 34 | 1.4 × 10−12 | | HOMA-IR | 1.1 (0.9–1.2) | 2.5 (2.2–2.8) | 2.0 (1.6–2.4) | 2.3 (2.0–2.7) | 1.6 × 10−12 | | HOMA-β | 89 (79–102) | 144 (128–162) | 39 (31–49) | 39 (31–49) | 1.5 × 10−21 |
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