Association between MYH9 and APOL1 Gene Polymorphisms and the Risk of Diabetic Kidney Disease in Patients with Type 2 Diabetes in a Chinese Han Population

Table 1

Demographics and clinical characteristics of T2DM patients with and without kidney diseases.

Variables	DKD ()^a	DM ()^a
Age (y)	63.0 (55.0, 72.0)	61.0 (54.0, 68.0)	0.002
Sex, male (%)	63.4 (192/303)	58.0 (211/364)	0.156
BMI (kg/m^2)	25.82 (24.0, 28.23)	25.29 (23.2, 27.78)	0.008
Duration of diabetes (y)	15.0 (9.0, 21.0)	13.0 (10.0, 18.0)	0.039
History of hypertension (%)	77.56 (235/303)	48.08 (175/364)	<0.001
Current smoking (%)	33.0 (100/303)	26.6 (97/364)	0.073
SBP (mmHg)	138.0 (125.0, 150.0)	126.0 (120.0, 139.8)	<0.001
DBP (mmHg)	80.0 (75.0, 84.0)	80.0 (70.0, 80.0)	0.026
A1C (%)	8.0 (6.7, 9.35)	7.5 (6.5, 9.2)	0.037
Hcy (μmol/L)	13.89 (11.09, 17.22)	11.49 (9.54, 13.62)	<0.001
TC (mmol/L)	4.21 (3.49, 5.06)	4.17 (3.55, 4.92)	0.51
HDL-C (mmol/L)	0.96 (0.78, 1.18)	1.02 (0.85, 1.24)	0.004
LDL-C (mmol/L)	2.34 (1.86, 3.05)	2.38 (1.91, 2.96)	0.74
TG (mmol/L)	1.74 (1.22, 2.57)	1.43 (1.0, 2.17)	<0.001

Abbreviations: A1C, hemoglobin A1C; BMI, body mass index; DBP, diastolic blood pressure; Hcy, homocysteine; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride. ^aData are shown as median (interquantile range) or %. indicates statistical significance.