Association between MYH9 and APOL1 Gene Polymorphisms and the Risk of Diabetic Kidney Disease in Patients with Type 2 Diabetes in a Chinese Han Population

Table 2

Genotype and allele frequency of SNPs rs3752462 and rs136161 between DKD patients () and DM controls ().

	Genotypes, n (%)					Alleles, n (%)
rs3752462	TT	TC	CC	HWE value	P	T	C	P
DM	227 (62.4%)	115 (31.6%)	22 (6.0%)	0.155	0.004	569 (57.1%)	159 (42.9%)	0.002^,∆
DKD	150 (49.5%)	128 (42.2%)	25 (8.3%)	0.752		428 (70.6%)	178 (29.4%)
rs136161	CC	CG	GG	HWE value	P	C	G	P
DM	213 (58.5%)	126 (34.6%)	25 (6.9%)	0.287	0.944	552 (75.8%)	176 (24.2%)	0.751
DKD	180 (59.4%)	104 (34.3%)	19 (6.3%)	0.449		464 (76.6%)	142 (23.4%)

; ∆ indicates statistical significance by Holm-Bonferroni correction; HWE: Hardy-Weinberg equilibrium.