Association between MYH9 and APOL1 Gene Polymorphisms and the Risk of Diabetic Kidney Disease in Patients with Type 2 Diabetes in a Chinese Han Population
Table 4
The combined effect of MYH9 rs3752462 and APOL1 rs136161 polymorphisms on DKD.
Genotypes
DKD
DM
Without adjustment
With adjustment¶
rs3752462
rs136161
303
364
OR (95% CI)
P
OR (95% CI)
P
TT
CC
89
134
1#
—
1#
—
TT
CG + GG
61
93
0.988 (0.649–1.503)
0.953
1.039 (0.679–1.588)
0.861
TC
CC
76
66
1.734 (1.134–2.652)
0.011
1.732 (1.128–2.660)
0.012
TC
CG + GG
52
49
1.598 (0.995–2.565)
0.052
1.596 (0.989–2.575)
0.055
CC
CC
15
13
1.737 (0.789–3.826)
0.170
1.923 (0.864–4.283)
0.109
CC
CG + GG
10
9
1.673 (0.654–4.281)
0.283
1.736 (0.669–4.503)
0.257
#Reference category (odds ratio, 1.0); ¶Adjustment for age and gender; value < 0.05.
