Inflammatory Markers in Older Women with a History of Gestational Diabetes and the Effects of Weight Loss
Table 1
Baseline body composition, glucose metabolism, and inflammation.
NGT ()
IGT/T2DM ()
Age (year)
50 (2)
52 (2)
Weight (kg)
85.9 (4.4)
85.1 (3.0)
Body mass index (kg/m2)
32.2 (1.5)
32.0 (0.9)
Percent body fat
46.1 (1.7)
45.4 (1.4)
Fat mass (kg)
39.5 (2.7)
38.3 (2.5)
Fat-free mass (kg)
45.9 (2.2)
47.3 (2.6)
VO2max (L/min)
1.93 (0.10)
1.72 (0.09)
Visceral fat (cm2)
150.2 (22.9)
127.7 (10.9)a
Subcutaneous abdominal fat (cm2)
457.3 (38.2)
484.9 (42.6)
Fasting glucose (mmol/L)
5.2 (0.1)
6.3 (0.4)
Glucose at 120 min (mmol/L)
5.9 (0.5)
11.1 (0.6)c
Fasting insulin (pmol/L)
76 (13)
107 (15)
GAUC (mmol/L/120 min)
862 (25)
1231 (57)c
IAUC (pmol/L/120 min)
55,700 (9209)
56,794 (9954)
Glucose utilization (μmol/kg/min)
31.9 (4.6)
17.7 (2.4)b
Glucose utilization (μmol/kgFFM/min)
57.9 (7.2)
63.8 (3.1)a
TNFα (pg/mL)
2.93 (1.92)
1.51 (0.36)
TNFR1(μg/mL)
808.9 (84.7)
744.9 (48.5)
IL-6 (pg/mL)
2.08 (0.30)
2.38 (0.52)
SAA (μg/mL)
43.1 (9.65)
64.7 (37.1)
Values are mean (SEM). Baseline differences tested between groups: ,, and . NGT: normal glucose tolerance; IGT/T2DM: impaired glucose tolerance/type 2 diabetes mellitus; VO2max: maximum oxygen uptake; GAUC: glucose area under the curve; IAUC: insulin area under the curve.
