Research Article
Glomerular Filtration Rate and/or Ratio of Urine Albumin to Creatinine as Markers for Diabetic Retinopathy: A Ten-Year Follow-Up Study
Table 6
Multivariate analysis using Cox’s proportional regression analysis of STDR and DME.
| | STDR | DME |
| | Variables | Significance | Significance | | Hazard ratio (95% CI) | Hazard ratio (95% CI) |
| | Current age | | | | HR 0.991 (0.984–0.999) | HR 0.993 (0.986–1.000) |
| | Sex | | | | HR 0.644 (0.531–0.781) | HR 0.655 (0.539–0.794) |
| | Insulin treatment | | | | HR 1.313 (1.123–1.535) | HR 1.308 (1.117–1.530) |
| | Arterial hypertension | | | | HR 2.128 (1.726–2.623) | HR 2.126 (1.721–2.626) |
| | HbA1c | | | | HR 3.230 (2.378–4.387) | HR 3.194 (2.350–4.340) |
| | eGFR < 60 ml/min/1.73 m2 | | | | HR 1.097 (0.899–1.979) | HR 1.033 (0.877–1.972) |
| | UACR ≥ 30 mg/g | | | | HR 2.099 (1.163–3.072) | HR 1.978 (1.237–2.901) |
| | UACR ≥ 300 mg/g and eGFR < 30 ml/min/1.73 m2 | | | | HR 3.174 (2.140–4.708) | HR 3.190 (2.150–4.732) |
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Hazard ratio (95% confidence interval). STDR: sight threatening diabetic retinopathy; DME: diabetic macular edema. Hazard ratio (95%CI). |
