Four Plasma Glucose and Insulin Responses to a 75 g OGTT in Healthy Young Japanese Women

Table 2

Glucose metabolism of women by insulin and glucose response type.

Type	Normal	Insulin-late	Insulin- & glucose-late	Insulin-very late
Number	39	11	7	5
Plasma glucose (mg/dL)
0 min	83.4 ± 6.1	83.5 ± 4.5	83.0 ± 5.7	86.0 ± 3.0
30 min	117.0 ± 22.2^a	133.2 ± 10.9^a,b	133.1 ± 12.0^a,b	147.4 ± 22.1^b
60 min	89.2 ± 22.2^a	112.1 ± 14.5^b	142.0 ± 15.6^b	139.0 ± 29.4^b
120 min	89.3 ± 14.8^a	88.8 ± 13.5^a,b	92.0 ± 9.4^a,b	114.7 ± 24.8^b
Immunoreactive insulin (μU/mL)
0 min	6.2 ± 2.7^a	5.7 ± 1.9^a	3.2 ± 0.8^b	5.7 ± 1.4^a,b
30 min	74.1 ± 33.4^a	47.2 ± 18.6^a	38.1 ± 11.1^b	44.5 ± 24.0^a,b
60 min	42.3 ± 23.7^a	65.9 ± 26.0^b	53.5 ± 19.2^a,b	45.0 ± 12.9^a,b
120 min	36.1 ± 21.5^a	40.6 ± 22.1^a,b	35.6 ± 15.6^a,b	68.0 ± 14.5^b
HbA1c (%)	5.18 ± 0.27	5.12 ± 0.22	5.05 ± 0.20	5.10 ± 0.17
HOMA-IR	1.32 ± 0.63^a	1.23 ± 0.43^a	0.66 ± 0.18^b	1.20 ± 0.26^a,b
Insulinogenic index	2.50 ± 2.14^a	1.10 ± 0.94^b	0.76 ± 0.38^b	0.59 ± 0.25^b
HOMA-β	115 ± 47^a	108 ± 44^a,b	65 ± 33^b	92 ± 35^a,b
QUICKI	0.38 ± 0.03^a	0.38 ± 0.03^a	0.42 ± 0.02^b	0.38 ± 0.02^a,b
AUC-glucose (hr·mg/dL)	191 ± 31^a	216 ± 21^a,b	240 ± 11^b	253 ± 53^b
AUC-insulin (hr.μU/mL)	91.9 ± 44.8	94.7 ± 38.5	77.8 ± 27.3	88.0 ± 29.8

Values are means ± SD. HOMA-IR: homeostasis model assessment-insulin resistance; HOMA-β: homeostasis model assessment for β-cell function; QUICKI: quantitative insulin sensitivity check index; AUC: area under the curve. The values for each index with different superscript letters are statistically different at by comparing different patterns of each time, as determined by Dunn’s multiple comparison test.