A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes

Figure 5

Pancreatic insulin content in low and high fat-fed mice treated with three consecutive once-daily doses of vehicle or 30, 50, or 75 mg/kg STZ. Data are . Low fat—vehicle, ; low fat—30 mg/kg STZ, ; low fat—50 mg/kg STZ, ; high fat—vehicle, ; high fat—30 mg/kg STZ, ; high fat—50 mg/kg STZ, ; high fat—75 mg/kg STZ, . versus low fat—vehicle, versus high fat—vehicle.