Vitamin D-Binding Protein Clearance Ratio Is Significantly Associated with Glycemic Status and Diabetes Complications in a Predominantly Vitamin D-Deficient Population

Table 2

Spearman rank correlations of VDBP clearance ratio with metabolic and other variables.

Variable	Correlation coefficient
Age (years)	0.28	0.001
WC (cm)	0.18	0.028
SBP (mmHg)	0.20	0.015
DBP (mmHg)	0.26	0.001
LDL-C (mmol/L)	−0.04	0.623
HDL-C (mmol/L)	−0.14	0.080
ALP (IU/L)	0.05	0.527
ALT (IU/L)	0.08	0.352
TG (mmol/L)	0.19	0.021
TC (mmol/L)	−0.01	0.908
Serum creatinine (μmol/L)	0.10	0.203
Total protein (g/L)	0.07	0.386
Albumin (g/L)	−0.14	0.093
Corrected calcium (mmol/L)	0.09	0.262
B%	−0.27	0.002
S%	−0.07	0.426
HOMA-IR	−0.01	0.948
Insulin (μIU/mL)	0.06	0.486
Glucose (mmol/L)	0.31	<0.001
HbA1c (%)	0.35	<0.001
Vitamin D (nmol/L)	0.02	0.794
Plasma VDBP (mg/mL)	−0.13	0.128
Vitamin D/albumin	0.03	0.695
Vitamin D/VDBP	0.08	0.333
Urine VDBP (ng/mL)	0.95	<0.001
Urine microalbumin (mg/L)	0.31	<0.001
Urine microalbumin/creatinine (mg/g)	0.44	<0.001

WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; LDL-C: low-density lipoprotein; HDL-C: high-density lipoprotein; ALP: alkaline phosphate; ALT: alanine aminotransferase; TG: triglyceride; TC: total cholesterol; B%: beta cell function; S%: insulin sensitivity; HOMA-IR: homeostasis model assessment of insulin resistance; HbA1c: hemoglobin A1c; plasma VDBP: plasma vitamin D-binding protein; vitamin D/VDBP: vitamin D-to-vitamin D-binding protein ratio; urine VDBP: urine vitamin D-binding protein.