Journal of Diabetes Research / 2018 / Article / Fig 2

Review Article

Application of Metabolomics to Study Effects of Bariatric Surgery

Figure 2

Summary of pathway analysis. The following are the top 25 identified statistically significant pathways: 1: aminoacyl-tRNA biosynthesis; 2: glycine, serine, and threonine metabolism; 3: nitrogen metabolism; 4: phenylalanine metabolism; 5: cysteine and methionine metabolism; 6: citrate cycle (TCA cycle); 7: taurine and hypotaurine metabolism; 8: valine, leucine, and isoleucine biosyntheses; 9: propanoate metabolism; 10: nicotinate and nicotinamide metabolism; 11: alanine, aspartate, and glutamate metabolism; 12: arginine and proline metabolism; 13: synthesis and degradation of ketone bodies; 14: pyrimidine metabolism; 15: methane metabolism; 16: glutathione metabolism; 17: glyoxylate and dicarboxylate metabolism; 18: pyruvate metabolism; 19: purine metabolism; 20: pantothenate and CoA biosyntheses; 21: D-glutamine and D-glutamate metabolism; 22: valine, leucine, and isoleucine degradation; 23: butanoate metabolism; 24: glycolysis or gluconeogenesis; 25: linoleic acid metabolism.