Impaired Glucose Metabolisms of Patients with Obstructive Sleep Apnea and Type 2 Diabetes
Table 1
Characteristics of OSA with non-T2DM and OSA with T2DM.
Parameters
Non-T2DM ()
T2DM ()
Male
24 (72.73)
17 (85.00)
0.486
Female
9 (27.27)
3 (15.00)
Age (years)
44.03 ± 11.60
47.70 ± 10.57
0.254
Weight (kg)
84.27 ± 13.58
87.94 ± 11.69
0.321
Height (m)
1.71 ± 0.08
1.73 ± 0.06
0.248
BMI (kg/m2)
28.86 ± 3.50
29.36 ± 2.94
0.597
Waist circumference (cm)
105.00 (89.50, 108.00)
102.00 (97.00, 109.00)
0.508
Neck circumference (cm)
45.00 (39.00, 48.00)
45.00 (41.00, 46.00)
0.804
Comorbidities
Obesity
19 (57.58)
15 (75.00)
0.200
Hypertension
28 (84.85)
13 (65.00)
0.182
Dyslipidemia
24 (72.72)
18 (90.00)
0.249
NAFLD
30 (90.91)
20 (100.00)
0.438
Sleep characteristics
TST (min)
382.12 ± 59.48
391.60 ± 51.00
0.556
Sleep efficiency (%)
82.80 ± 12.25
83.76 ± 9.51
0.768
Stage N1/TST (%)
17.88 ± 11.92
21.34 ± 13.66
0.337
Stage N2/TST (%)
62.23 ± 10.10
61.83 ± 15.25
0.910
Stage N3/TST (%)
0 (0, 5.95)
0 (0, 2.81)
0.787
Stage REM/TST (%)
17.11 ± 6.71
15.92 ± 4.65
0.487
AHI (events/h)
31.60 (19.55, 72.05)
43.70 (21.90, 73.03)
0.633
N-REM AHI (events/h)
27.60 (18.25, 73.05)
40.25 (22.53, 74.90)
0.430
REM AHI (events/h)
53.90 (22.45, 65.25)
48.45 (25.13, 63.83)
0.577
Nadir SpO2 (%)
82.00 (73.00, 87.00)
74.00 (50.50, 86.00)
0.139
Mean SpO2 (%)
95.00 (93.00, 96.35)
93.00 (87.50, 95.88)
0.075
ODI (events/h)
21.40 (11.00, 73.80)
38.30 (17.50, 73.68)
0.271
Biochemical parameters
FBG (mmol/L)
5.41 ± 0.58
8.82 ± 1.86
≤0.001
Cholesterol (mmol/L)
4.84 ± 0.73
4.44 ± 1.04
0.111
Triglycerides (mmol/L)
2.25 ± 1.32
2.30 ± 0.91
0.889
HDL cholesterol (mmol/L)
1.14 ± 0.22
1.07 ± 0.18
0.221
LDL cholesterol (mmol/L)
3.09 ± 0.68
2.84 ± 0.85
0.245
Continuous data with normal distribution are presented as mean ± SD, continuous data with nonnormal distribution are presented as median (first quartile, third quartile), and noncontinuous data are presented as number (%). T2DM: type 2 diabetes mellitus; BMI: body mass index; NAFLD: nonalcoholic fatty liver disease; TST: total sleep time; AHI: apnea-hypopnea index; REM: rapid eye movement; N-REM: nonrapid eye movement; SpO2: arterial oxygen saturation; ODI: oxygen desaturation index; FBG: fasting blood glucose; HDL: high-density lipoprotein; LDL: low-density lipoprotein ().
