Research Article

Genetic Variability of the Glucose-Dependent Insulinotropic Peptide Gene Is Involved in the Premature Coronary Artery Disease in a Chinese Population with Type 2 Diabetes

Table 11

Genotype distributions of rs2291725 in smoking patients in dominant inheritance mode.

GeneSNPs genotypeCAD positive n (%)CAD negative n (%)OR (95% CI)OR (95% CI)

GIPrs2291725
C/C91 (46.2)30 (32.3)1.803 (1.075–3.024)0.0251.500 (1.052–2.140)0.025
C/T + T/T106 (53.8)63 (67.7)

OR, 95% CI, and p were calculated by logistic regression analysis after adjustment for other known CAD risk factors (age, BMI, dyslipidemia history, hypertension history, and diabetic duration).