Genetic Variability of the Glucose-Dependent Insulinotropic Peptide Gene Is Involved in the Premature Coronary Artery Disease in a Chinese Population with Type 2 Diabetes

Table 12

The association of accumulative risk score with CAD risk in T2D patients.

Risk factors	CAD positive n (%)	CAD negative n (%)	OR (95% CI)
0	3 (0.7)	10 (3.6)	1	1
1	28 (7.2)	42 (15.2)	2.222 (0.561–8.798)	0.247
2	79 (20.3)	81 (29.4)	3.251 (0.862–12.254)	0.068
3	120 (30.8)	80 (29.0)	5.000 (1.335–18.733)	0.009
4	117 (30.0)	50 (18.1)	7.800 (2.059–29.552)	0.001
5	43 (11.0)	13 (4.7)	11.026 (2.634–46.146)	<0.001

Accumulated risk factors included risk genotype of rs2291725 (C/C) and rs8078510 (G/G), age, sex (male ≥ 55 y, female ≥ 65 y), smoking, and BMI ≥ 24 kg/m².