Genetic Variability of the Glucose-Dependent Insulinotropic Peptide Gene Is Involved in the Premature Coronary Artery Disease in a Chinese Population with Type 2 Diabetes

Table 5

The association of SNPs with CAD risk in dominant inheritance mode.

Gene	SNPs genotype	CAD positive n (%)	CAD negative n (%)	OR (95% CI)		OR (95% CI)
GIP	rs2291725
	C/C	187 (48.6)	102 (37.5)
	C/T + T/T	198 (51.4)	170 (62.5)	0.635 (0.463–0.872)	0.005	0.769 (0.626–0.945)	0.013
	rs8078510
	G/G	281 (73.2)	174 (64.7)
	G/A + A/A	103 (26.8)	95 (35.3)	0.671 (0.479–0.940)	0.020	0.762 (0.612–0.949)	0.015

OR, 95% CI, and p were calculated by logistic regression analysis after adjustment for other known CAD risk factors (age, BMI, smoking status, dyslipidemia history, hypertension history, and diabetic duration).