The Effects of Momordica balsamina Methanolic Extract on Kidney Function in STZ-Induced Diabetic Rats: Effects on Selected Metabolic Markers
Table 2
Comparison of plasma biochemical parameters and urinary electrolytes of nondiabetic controls, diabetic controls, and diabetic rats treated with MB, metformin, and insulin during a 5-week study ( in each group). Values are expressed as .
Parameters
Groups
NC
DC
MB
INS
MTF
Urinary Na+ (mmol/L)
66.8 ± 1.2
42.3 ± 3.5#
53.7 ± 1.3
38.2 ± 1.2
66.0 ± 2.9
Plasma Na+ (mmol/L)
120.3 ± 3.3
134.0 ± 2.0#
121.5 ± 4.2
133.2 ± 1.3
121.7 ± 1.4
Urinary K+ (mmol/L)
45.5 ± 1.7
25.5 ± 2.1#
53.7 ± 1.3
38.2 ± 3.3
55.5 ± 4.1
Plasma K+ (mmol/L)
9.9 ± 1.3
7.6 ± 0.6#
7.9 ± 0.3
9.5 ± 0.7
8.4 ± 0.4
Urinary urea (mmol/L)
654.3 ± 6.8
117.8 ± 4.8#
315.3 ± 5.8
356 ± 9.9
351 ± 8.0
Plasma urea (mmol/L)
4.9 ± 0.3
17.5 ± 1.3#
7.0 ± 0.6
7.6 ± 0.8
6.4 ± 0.9
Urinary albumin (g/L)
1.7 ± 0.2
3.5 ± 0.4#
3.2 ± 0.7
4.2 ± 0.7
4.7 ± 1.1
Plasma albumin (g/L)
16.5 ± 1.0
12.3 ± 0.6#
13.2 ± 0,6
14.3 ± 0.7
14.3 ± 1.3
Urinary creatinine (μmol/L)
9.9 ± 0.7
14.9 ± 0.3#
10.4 ± 0.2
8.1 ± 0.4
10.8 ± 0.2
Creatinine (μmol/L)
32.5 ± 1.3
45.8 ± 1.1#
29.8 ± 1.0
34.8 ± 1.9
28.2 ± 0.8
Aldosterone (pg/mL)
0.2 ± 0.02
0.4 ± 0.1#
0.3 ± 0.4
0.4 ± 0.2
0.2 ± 0.1
by comparison with nondiabetic control; by comparison with diabetic control.
