Relationship of Hyperglycaemia, Hypoglycaemia, and Glucose Variability to Atherosclerotic Disease in Type 2 Diabetes

Table 5

Continuous glucose-monitoring findings of subjects with and without macrovascular disease.

Variable	No macrovascular disease ()	Macrovascular disease ()	value
Highest value (mmol/L)^†	13.4 (11.3–15.85)	13.0 (11.3–15)	0.35
Lowest value (mmol/L)^†	4.4 (3.2–5.25)	3.7 (2.8–5)	0.09
Mean blood glucose (mmol/L)^†	7.6 (6.85–9.0)	7.3 (6.6–8.4)	0.3
Standard deviation (mmol/L)^†	3.0 (1.3–2.3)	1.8 (1.5–2.4)	0.9
Number of high excursions^†	8 (6–10)	8 (5–10)	0.49
Number of low excursions^†	0 (0–2)	1 (0–2)	0.10
AUC above 7.8 mmol/L^†	0.64 (0.24–1.76)	0.57 (0.21–1.35)	0.39
AUC below 3.9 mmol/L^†	0 (0–0.01)	0 (0–0.03)	0.05
Duration during 72 hr period with BG above 7.8 mmol/L (%)^†	37 (18.5–66.5)	35 (20–58)	0.39
Duration during 72 hr period with BG within 3.9–7.8 mmol/L (%)^†	58 (31.5–79)	60 (41–77)	0.63
Duration during 72 hr period with BG below 3.9 mmol/L (%)^†	0 (0-1)	1 (0–5)	0.02

Values are expressed as number (%) of patients or ^†median (IQR). AUC: area under curve.