Sex Differences in the Prevalence and Modulators of Sleep-Disordered Breathing in Outpatients with Type 2 Diabetes
Table 3
Linear regression analysis: factors associated with AHI in the total population, in 267 women and in 412 men.
Variable
Univariable analysis
Multivariable analysis
B (95% CI)
value
B (95% CI)
value
Total population ()
Female sex
−4.75 (−6.74, −2.76)
<0.001
−3.54 (−6.06, −1.02)
0.006
Age [per 10 years]
1.70 (0.59, 2.81)
0.003
2.55 (1.40, 3.70)
<0.001
BMI [per 5 units]
2.99 (2.10, 3.88)
<0.001
3.48 (2.53, 4.44)
<0.001
Waist-hip ratio [per 0.1 unit]
4.48 (3.25, 5.71)
<0.001
2.35 (0.77, 3.94)
0.004
Systolic BP
0.08 (0.03, 0.13)
0.004
0.02 (−0.04, 0.07)
0.508
T2D duration
0.09 (−0.04, 0.21)
0.165
−0.004 (−0.13, 0.12)
0.952
Women ()
Age [per 10 years]
1.92 (0.49, 3.35)
0.009
2.35 (0.83, 3.87)
0.003
BMI [per 5 units]
2.00 (0.87, 3.13)
0.001
2.05 (0.88, 3.21)
0.001
Waist-hip ratio [per 0.1 units]
3.24 (1.13, 5.35)
0.003
2.29 (0.18, 4.40)
0.034
Systolic BP
0.08 (0.01, 0.16)
0.037
0.03 (−0.05, 0.11)
0.446
T2D duration
0.06 (−0.13, 0.25)
0.527
−0.02 (−0.02, 0.17)
0.826
Men ()
Age [per 10 years]
1.41 (−0.19, 3.01)
0.084
2.76 (1.09, 4.43)
0.001
BMI [per 5 units]
4.75 (3.45, 6.06)
<0.001
5.25 (3.73, 6.77)
<0.001
Waist-hip ratio [per 0.1 units]
4.92 (2.71, 7.12)
<0.001
1.59 (−0.77, 3.94)
0.185
Systolic BP
0.06 (−0.01, 0.14)
0.091
0.01 (−0.06, 0.09)
0.739
T2D duration
0.07 (−0.09, 0.23)
0.393
0.01 (−0.15, 0.17)
0.882
AHI = apnoea-hypopnoea index; B = unstandardized regression coefficient; 95% CI = 95% confidence interval; BMI = body mass index; T2D duration = duration of type 2 diabetes; BP = blood pressure.
