Extracellular Vesicles: A Novel Target for Exercise-Mediated Reductions in Type 2 Diabetes and Cardiovascular Disease Risk

Table 3

Most commonly used extracellular vesicles.

EV origin	Surface markers
Endothelium	CD31 ^+ /CD41 ^− (PECAM ^+ /ITGA2B ^− ); CD31^+/CD42^− (PECAM^+/GPIb^−); CD31 (PECAM (platelet cell adhesion molecule)); CD144 (VE cadherin (vascular endothelial cadherin)); CD146 (MCAM (melanoma cell adhesion molecule)); CD105 (endoglin); CD106 (VCAM (vascular cell adhesion molecule)); CD62E (E-selectin (endothelial-selectin))
Platelet	CD41 (ITGA2B (integrin alpha 2b)); CD42 (GPIb (glycoprotein Ib)); CD31 (PECAM (platelet cell adhesion molecule))
Leukocyte	CD45 (PTPRC (protein tyrosine phosphate receptor type C)); CD11b (ITGAM (integrin alpha M)); CD14 (coreceptor of lipopolysaccharide); CD16 (on surface of neutrophils, monocytes, and macrophages); CD62L (L-selectin (leukocyte selectin))
Red blood cell	CD235 (glycophorin A)