Research Article

There Is No Impact of Diabetes on the Endothelial Function of Chronic Kidney Disease Patients

Table 1

Clinic characteristics of the study population.

CKD group ()CKD-DM group ()

Age, years65.9 ± 13.964.1 ± 9.90.54
Male, (%)21 (56.8%)22 (59.5%)0.814
Hypertension, (%)35 (97.2%)34 (94.4%)0.555
Chronic kidney disease etiology, (%)<0.001
 Diabetes0 (0%)33 (89.2%)
 Undetermined19 (51.4%)1 (2.7%)
 Hypertension7 (18.9%)0
 Glomerulopathy5 (13.5%)0
 Others6 (16.2%)3 (8.1%)
Cardiovascular disease, (%)12 (32.4%)19 (51.4%)0.099
 Myocardial infarction1 (2.7%)7 (18.9%)0.025
 Myocardial revascularization0 (0%)4 (10.8%)0.04
 Cerebrovascular accident5 (13.5%)4 (10.8%)0.722
 Peripheral artery disease7 (18.9%)14 (37.8%)0.071
Drugs, (%)
 ACEI/ARB27 (75%)33 (91.7%)0.058
 Calcium channel blockers27 (75%)17 (47.2%)0.016
 Diuretics25 (69.4%)34 (94.4%)0.006
 Vasodilator2 (5.6%)7 (19.4%)0.075
 Lipid-lowering agents24 (68.6%)30 (85.7%)0.088
 Acetylsalicylic acid14 (38.9%)27 (73%)0.003
Systolic blood pressure, mmHg130 (125–140)140 (123.5–158.5)0.214
Diastolic blood pressure, mmHg80 (70–90)77 (70–84)0.343
Body mass index, kg/m227.7 ± 4.731.4 ± 5.70.004
Waist-hip circumference ratio0.97 ± 0.071.00 ± 0.060.032

ACEI = angiotensin-converting enzyme inhibitor; ARB = angiotensin receptor blocker.