Neurophysiological Evidence for a Compensatory Activity during a Simple Oddball Task in Adolescents with Type 1 Diabetes Mellitus

Figure 1

Individual ERP and VEP traces. Single subjects’ ERPs and VEPs are plotted as thick or thin lines for patients and controls, respectively. The columns correspond to the selected derivation of examined ERP/VEPs, and the subjects’ responses form the rows. The marked peaks were used for the statistical analysis. For the latency assessment, we used the middle marker; for amplitude, an average of two interpeak values (see Methods). There is an apparent increase in the area under curve of the P3b peak in the target ERP for patients, as we confirmed in the intergroup comparison (). Further, there is a slight but significant () time shift of the middle marker of the pattern-reversal VEPs—the P100 peak—for both stimulation patterns (PR-VEP 40 and 20).