Skeletal Status, Body Composition, and Glycaemic Control in Adolescents with Type 1 Diabetes Mellitus

Figure 3

Comparison of DXA parameters expressed as the mean (±SD) Z-score values (calculated according to age- and gender-dependent data for healthy subjects), including (a) bone mineral density and bone mineral content of the whole skeleton, relative bone strength ratio (TBBMC/LBM ratio), and (b) bone mineral density and bone mineral content of the lumbar spine, between T1DM patients with well-controlled glycaemia versus those with poorly controlled glycaemia. The dotted line represents the lowest level of the acceptable range of value in healthy subjects (Z-score = −2.0). -Value indicates significant differences between studied subgroups, adjusted for age, sex, disease duration, pubertal stage, insulin dose, height, weight, and physical activity level; NS, not significant. TBBMD — total body bone mineral density; TBBMC — total body bone mineral content; TBBMC/LBM — total body bone mineral content/lean body mass ratio; S24BMD — bone mineral density, lumbar spine L2–L4; S24BMC — bone mineral content, lumbar spine L2–L4; S24BMC/LBM — bone mineral content, lumbar spine L2–L4/lean body mass ratio.

(a)

(b)