Skeletal Status, Body Composition, and Glycaemic Control in Adolescents with Type 1 Diabetes Mellitus
Table 2
The Z-score values for DXA parameters in T1DM patients with well or poorly controlled glycaemia.
Variable (Z-scores)/1
± SD
SE
95% CI
Z TBBMD
−0.38 ± 0.95
0.12
−0.63; −0.14
0.003
Z TBBMC
−0.29 ± 0.97
0.13
−0.54; −0.03
0.027
Z LBM
−0.08 ± 0.90
0.12
−0.32; +0.15
0.483
Z S24BMD
−0.30 ± 1.06
0.14
−0.58; −0.03
0.031
Z S24BMC
−0.09 ± 0.99
0.13
−0.35; +0.16
0.461
Z TBBMC/LBM
−0.29 ± 0.97
0.13
−0.54; −0.04
0.025
Z S24BMC/LBM
+0.29 ± 1.16
0.15
−0.01; +0.59
0.055
Z FM/2
+0.38 ± 1.27
0.16
+0.05; +0.70
0.025
Z FM/LBM
+0.31 ± 0.99
0.13
+0.63; +0.57
0.018
(HbA1c < 8%)
Z TBBMD
−0.10 ± 0.97
0.17
−0.44; +0.23
0.535
Z TBBMC
+0.01 ± 1.02
0.18
−0.35; +0.37
0.959
Z LBM
+0.20 ± 0.90
0.15
−0.11; +0.52
0.197
Z S24BMD
−0.20 ± 1.16
0.20
−0.61; +0.20
0.321
Z S24BMC
+0.09 ± 1.06
0.18
−0.28; +0.46
0.618
Z TBBMC/LBM
−0.07 ± 0.96
0.17
−0.41; +0.27
0.677
Z S24BMC/LBM
+0.44 ± 1.20
0.21
+0.02; +0.86
0.039
Z FM/2
+0.36 ± 1.44
0.25
−0.14; +0.86
0.153
Z FM/LBM
+0.20 ± 1.05
0.18
−0.16; +0.57
0.266
(HbA1c ≥ 8%)
Z TBBMD
−0.74 ± 0,80
0.16
−1.07; −0.42
0.001
Z TBBMC
−0.67 ± 0.77
0.15
−0.98; −0.37
0.001
Z LBM
−0.45 ± 0.77
0.15
−0.77; −0.14
0,006
Z S24BMD
−0.43 ± 0.91
0.18
−0.80; −0.07
0.022
Z S24BMC
−0.34 ± 0.85
0.17
−0.68; +0.01
0.053
Z TBBMC/LBM
−0.58 ± 0.92
0.18
−0.95; −0.20
0.004
Z S24BMC/LBM
+0.10 ± 1.10
0.22
−0.35; +0.54
0.652
Z FM/2
+0.40 ± 1.03
0.20
−0.02; +0.81
0.060
Z FM/LBM
+0.45 ± 0.90
0.18
+0.09; +0.82
0.018
± SD: mean ± standard deviation; SE: standard error of the mean; 95% CI: confidence interval; -values were calculated with one-sample t-test compared to the hypothetical values of 0 (expected in healthy subjects); /1Z-scores for DXA parameters calculated according to age- and sex-dependent reference data for healthy subjects; /2Wilcoxon test TBBMD — total body bone mineral density; TBBMC — total body bone mineral content; LBM — lean body mass; FM — fat mass; S24BMD — bone mineral density, lumbar spine L2–L4; S24BMC — bone mineral content, lumbar spine L2–L4; S24BMC/LBM — bone mineral content, lumbar spine L2–L4/lean body mass ratio; TBBMC/LBM — total body bone mineral content/lean body mass ratio; FM/LBM — fat mass/lean body mass ratio.
