Review Article
Netrin as a Novel Biomarker and Its Therapeutic Implications in Diabetes Mellitus and Diabetes-Associated Complications
Figure 2
Schematic illustration of the possible molecular mechanism of anti-inflammatory actions of recombinant human Netrin-1 mediated through UNC5B and via commonest inflammatory signaling pathways and its potential role of affecting the progression of diabetic microvascular complications. PGE2: prostaglandin E2; TNF: tumor necrosis factor; COX: cyclooxygenase; PPAR: peroxisome proliferator-activated receptor; rhNetrin-1: recombinant human Netrin-1.