Contractile Protein Expression and Phosphorylation and Contractility of Gastric Smooth Muscles from Obese Patients and Patients with Obesity and Diabetes

Figure 4

CPI-17 expression and T38 phosphorylation in nondiabetic and diabetic gastric fundus and antrum smooth muscles. (a) Representative immunoblots of CPI-17 expression in nondiabetic and diabetic fundus (left panel, , each group) and nondiabetic and diabetic antrum muscles (right panel, , each group), 1 μg muscle lysate per lane. (b) CPI-17 expression relative to enteric γ-actin expression in nondiabetic and diabetic fundus and antrum smooth muscles. (c) Representative immunoblots of phosphorylated T38 in nondiabetic and diabetic fundus (left panel, , each group) and nondiabetic and diabetic antrum muscles (right panel, , each group), 1 μg muscle lysate per lane. (d) T38 phosphorylation relative to CPI-17 expression in nondiabetic and diabetic gastric fundus and gastric antrum smooth muscles. , , , and .

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