Intravitreal Bevacizumab Injection Attenuates Diabetic Retinopathy in Adult Rats with Experimentally Induced Diabetes in the Early Stage

Figure 1

Neuronal and vascular changes in the early stage of diabetes. (a–d) H&E staining of the retina in the NC, DM3w, DM6w, and DM9w groups. Black arrow indicates neuronal changes in which the ganglion cells appeared to be enlarged at the DM3w group but were condensed at the DM6w and DM9w groups. Blood vessels were dilated in diabetic retina notably at the DM6w and DM9w groups (asterisk). (e, f) Quantification of retinal thickness and ganglion cell number in the NC, DM3w, DM6w, and DM9w groups. Bar = 50 μm. and .

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