Journal of Diabetes Research / 2018 / Article / Fig 1

Research Article

Spironolactone Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Rats

Figure 1

Cardiac ultramicrostructure was preserved in SPR-treated rats. (a–c) Representative electron micrographs for mitochondria, myofibrils, and sarcoplasmic reticulum, respectively. In the NDC group, normal ultrastructure was observed in the heart tissue. Loss of cristae, irregular arrangement of myofibrils, and enlarged sarcoplasmic reticula were observed in the STZ + NS group. Pathological changes in the STZ + SPR group were significantly reduced compared to those of the diabetic group. Red, blue, and green arrows indicate mitochondria, myofibrils, and sarcoplasmic reticulum, respectively.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.