Astragalus membranaceus and Panax notoginseng, the Novel Renoprotective Compound, Synergistically Protect against Podocyte Injury in Streptozotocin-Induced Diabetic Rats

Figure 1

Effects of AG and NG on physical and biochemical parameters in diabetic rats. ACR in diabetic rats after treatment with AG and NG for 3 weeks (a) and 12 weeks (b). Blood glucose (c) after STZ injection. Serum creatinine (d), ALT (e), and KW/BW (f) after treatment with AG and NG for 12 weeks. ACR: albuminuria/creatinine ratio; ALT: alanine aminotransferase; KW/BW: kidney weight per body weight ratio; control: normal control rats; DN: STZ-induced diabetic rats; losartan: DN rats treated with losartan; AG: DN rats treated with Astragalus membranaceus; NG: DN rats treated with Panax notoginseng; AG+NG: DN rats treated with Astragalus membranaceus plus Panax notoginseng. Results were expressed as the (). vs. control group, vs. DN group, ^▲ vs. AG group, ^▼ vs. NG group.

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