Astragalus membranaceus and Panax notoginseng, the Novel Renoprotective Compound, Synergistically Protect against Podocyte Injury in Streptozotocin-Induced Diabetic Rats

Figure 6

Effects of AG and NG on the expression of Bax and Bcl-xl in diabetic rats. Representative photomicrographs of immunostaining (a) and western blots (e) for Bax and Bcl-xl in the glomeruli of kidney sections. Semiquantitative analyses of immunostaining for Bax (b) and Bcl-xl (c). Glomerular relative mRNA levels of Bax (d). Semiquantitative analyses of western blots for Bax (f) and Bcl-xl (g). Control: normal control rats; DN: STZ-induced diabetic rats; losartan: DN rats treated with losartan; AG: DN rats treated with Astragalus membranaceus; NG: DN rats treated with Panax notoginseng; AG+NG: DN rats treated with Astragalus membranaceus plus Panax notoginseng. Results were expressed as the . vs. control group, vs. DN group, ^▲ vs. AG group, ^▼ vs. NG group.

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