Cystatin C Is an Important Biomarker for Cardiovascular Autonomic Dysfunction in Chinese Type 2 Diabetic Patients

Table 1

Characteristics of patients with type 2 diabetes according to serum cystatin C tertiles.

	Tertile 1 (<0.78)	Tertile 2 (0.78–0.99)	Tertile 3 (>0.99)	Total	value
					Tertile 1 vs. 2	Tertile 1 vs. 3	Tertile 2 vs. 3
	52	57	52	161
Men (%)	21 (40)	22 (29)	18 (35)	61 (38)
Age (years)					<0.01	<0.01	<0.01
Diabetes duration (years)					0.08	<0.01	<0.01
BMI (kg/m^2)					0.07	0.24	0.53
SBP (mmHg)					0.96	0.96	0.91
DBP (mmHg)					0.08	0.01	0.39
HbA1c (%)					0.36	0.11	0.47
TC (mmol/l)					0.80	0.40	0.54
TG (mmol/l)					0.93	0.17	0.13
HDL-C (mmol/l)					0.66	0.30	0.13
LDL-C (mmol/l)					0.89	0.45	0.51
B2-MG (μg/l)					0.22	0.69	0.42
Cr (μmol/l)					0.07	<0.01	<0.01
eGFR (ml/min/1.73 m^2)					<0.01	<0.01	<0.01
FBG (mmol/l)					0.33	0.02	0.18
UA (μmol/l)					0.48	<0.01	<0.01
SDNN (ms)					0.51	<0.01	<0.01
SDANN (ms)					0.56	<0.01	<0.01
LogRMSSD (ms)					0.40	0.92	0.45
LogPNN50 (%)					0.55	0.25	0.55
LogLF (ms^2)					0.60	0.02	0.05
LogHF (ms^2)					0.82	0.05	0.07
LogLF/HF					0.42	0.19	0.60
CysC (mg/l)

BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1c: hemoglobin A1c; TC: total cholesterol; TG: triglyceride; HDL-C: HDL-cholesterol; LDL-C: LDL-cholesterol; Cr: creatinine; eGFR: estimated glomerular filtration rate; FBG: fasting blood glucose; UA: uric acid; β2-MG: β2-microglobulin; CysC: cystatin C.