Cigarette Smoking Is Negatively Associated with the Prevalence of Type 2 Diabetes in Middle-Aged Men with Normal Weight but Positively Associated with Stroke in Men
Table 3
Association between cigarette smoking and T2DM in men stratified by obesity ().
Subgroup
Model 1
Model 2
Model 3
OR
OR
OR
Never-smoker
1
1
1
1-19 pack-years
0.39 (0.28-0.54)
<0.001
0.46 (0.32-0.66)
<0.001
0.44 (0.30-0.63)
<0.001
≥20 pack-years
0.42 (0.31-0.59)
<0.001
0.47 (0.33-0.67)
<0.001
0.45 (0.32-0.64)
<0.001
Never-smoker
1
1
1
1-19 pack-years
0.65 (0.45-0.92)
0.016
0.88 (0.60-1.29)
0.524
0.87 (0.59-1.27)
0.467
≥20 pack-years
0.74 (0.54-1.03)
0.072
1.03 (0.72-1.48)
0.856
1.01 (0.71-1.44)
0.959
Never-smoker
1
1
1
1-19 pack-years
0.40 (0.28-0.56)
<0.001
0.50 (0.34-0.73)
<0.001
0.47 (0.32-0.69)
<0.001
≥20 pack-years
0.56 (0.40-0.78)
0.001
0.69 (0.48-0.99)
0.047
0.63 (0.44-0.91)
0.013
Never-smoker
1
1
1
1-19 pack-years
0.60 (0.44-0.84)
0.003
0.80 (0.56-1.14)
0.223
0.81 (0.57-1.16)
0.257
≥20 pack-years
0.56 (0.41-0.76)
<0.001
0.73 (0.52-1.02)
0.065
0.72 (0.51-1.01)
0.060
Never-smoker
1
1
1
1-19 pack-years
0.47 (0.36-0.60)
<0.001
0.61 (0.46-0.81)
0.001
0.59 (0.45-0.78)
<0.001
≥20 pack-years
0.58 (0.46-0.74)
<0.001
0.75 (0.58-0.98)
0.033
0.71 (0.54-0.92)
0.010
Never-smoker
1
1
1
1-19 pack-years
0.72 (0.38-1.37)
0.312
0.85 (0.43-1.69)
0.639
0.79 (0.37-1.68)
0.534
≥20 pack-years
0.37 (0.18-0.76)
0.007
0.47 (0.22-1.03)
0.059
0.45 (0.20-1.01)
0.052
Model 1: no adjusted variables. Model 2: adjusted for age, BMI, gender, educational level, physical activity, alcohol consumption, and family history of diabetes. Model 3: adjusted for Model 2 plus SBP, DBP, TG, TC, HDL-C, and LDL-C.
