Von Hippel-Lindau (VHL) Protein Antagonist VH298 Improves Wound Healing in Streptozotocin-Induced Hyperglycaemic Rats by Activating Hypoxia-Inducible Factor- (HIF-) 1 Signalling

<div>Immunohistochemical staining of CD31 in the wound area. 10x images showed more CD31-positive area (brown) in the VH298-treated wound, and 40x images showed more CD31-positive microvessels (brown) in the VH298-treated wound especially at the middle stage (14 days) of the wound healing process. Quantitative analysis showed more CD31-positive clusters in the VH298-treated group at all three time points. 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Journal of Diabetes Research

fig5

Figure 5

Figure 5: Von Hippel-Lindau (VHL) Protein Antagonist VH298 Improves Wound Healing in Streptozotocin-Induced Hyperglycaemic Rats by Activating Hypoxia-Inducible Factor- (HIF-) 1 Signalling 

Figure 5 | Von Hippel-Lindau (VHL) Protein Antagonist VH298 Improves Wound Healing in Streptozotocin-Induced Hyperglycaemic Rats by Activating Hypoxia-Inducible Factor- (HIF-) 1 Signalling 