Research Article

Glycated Serum Protein Genetics and Pleiotropy with Cardiometabolic Risk Factors

Table 2

Phenotypic and genetic correlations between the glycated serum protein metrics and cardiometabolic traits measured in the Jirel pedigree.

Trait pairsPhenotypic correlationGenetic correlation
(SE) value (SE) value

GSP-SBP0.089 (0.024)-0.027 (0.166)0.872
GSP-DBP0.067 (0.024)0.0056-0.053 (0.161)0.742
GSP-BMI0.047 (0.024)0.0520.017 (0.122)0.891
GSP-TC0.144 (0.024)0.351 (0.149)0.025
GSP-HDLC-0.019 (0.024)0.424-0.177 (0.161)0.273
GSP-LDLC0.096 (0.024)0.263 (0.136)0.057
%GA-SBP0.066 (0.024)0.0062-0.069 (0.177)0.689
%GA-DBP0.020 (0.024)0.402-0.140 (0.172)0.407
%GA-BMI0.006 (0.024)0.796-0.002 (0.128)0.988
%GA-TC0.035 (0.024)0.1480.289 (0.163)0.077
%GA-HDLC-0.106 (0.024)-0.238 (0.166)0.162
%GA-LDLC-0.021 (0.024)0.3820.072 (0.146)0.623

SE: standard error. Additive genetic heritability estimates (: 0.149 to 0.536) for all cardiometabolic traits were significant ( values: to ).