Table 3: TCSS as dependent variable in multiple stepwise regression analysis.

Unstandardized coefficientsStandardized coefficients value95% confidence interval for
Std. errorBetaLower boundUpper bound

Constant9.1171.1447.9670.0006.85111.383
Duration0.2420.0410.4415.9750.0000.1620.322
Genomic DNA methylation-16.4343.949-0.300-4.1620.000-24.253-8.615
eGFR-0.0270.008-0.253-3.4130.001-0.043-0.011

In multiple stepwise regression analysis, TCSS, as dependent variable, and the other 8 variables, age, duration, BMI, CRP, UACR, UA, eGFR, and genomic DNA methylation, as independent variables, were included in the same model. Only three variables, duration, genomic DNA methylation, and eGFR, were the risk factors of TCSS ().