Nrf2-Heme Oxygenase-1 Attenuates High-Glucose-Induced Epithelial-to-Mesenchymal Transition of Renal Tubule Cells by Inhibiting ROS-Mediated PI3K/Akt/GSK-3β Signaling
ROS regulation in human HK2 cells by SFN under high-glucose stress (assay by FACScan). High glucose induces an increase of intracytoplasmic ROS in human HK2 cells, but SFN treatment shows a left-shift pattern of the ROS curve.
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