Effect of Baoshenfang Formula on Podocyte Injury via Inhibiting the NOX-4/ROS/p38 Pathway in Diabetic Nephropathy
Table 2
Effect of BSF on biochemical indexes of DKD.
Groups
Control
BSF
value
Sample size
39
40
—
Female sex (%)a
20 (51.3%)
18 (45.0%)
>0.05
Age (years)b
62.95 ± 7.24
63.35 ± 8.02
>0.05
HbA1c (%)b (week 0)
7.81 ± 1.67
7.96 ± 1.40
>0.05
HbA1c (%)b (week 12)
6.47 ± 1.92
6.46 ± 0.74
>0.05
Total cholesterol (mmol/l)b (week 0)
6.04 ± 1.45
5.87 ± 1.14
>0.05
Total cholesterol (mmol/l)b (week 12)
4.59 ± 0.90
4.44 ± 0.87
>0.05
Triglyceride (mmol/l)b (week 0)
2.31 ± 0.89
2.29 ± 0.93
>0.05
Triglyceride (mmol/l)b (week 12)
1.64 ± 0.45
1.54 ± 0.38
>0.05
Serum albumin (g/l)b (week 0)
28.6 ± 1.4
28.3 ± 1.7
>0.05
Serum albumin (g/l)b (week 12)
33.2 ± 2.7
38.0 ± 2.4
<0.05
Serum creatinine (μmol/l)b (week 0)
121.6 ± 10.1
124.6 ± 13.0
>0.05
Serum creatinine (μmol/l)b (week 12)
115.6 ± 10.1
94.9 ± 13.0
<0.05
Blood urea nitrogen (mmol/l)b (week 0)
7.5 ± 0.4
7.6 ± 0.7
>0.05
Blood urea nitrogen (mmol/l)b (week 12)
6.7 ± 0.5
5.6 ± 0.3
<0.05
24 h urinary protein (g)b (week 0)
3.4 ± 1.9
3.48 ± 2.1
>0.05
24 h urinary protein (g)b (week 12)
3.18 ± 1.94
2.55 ± 1.67
<0.05
aThe data are expressed as counts (%), and the P value for the between-group difference is calculated from the Wilcoxon rank sum test. bThe data are expressed as the , and the P value for the two group comparisons is calculated using an independent-sample -test.