Research Article

Combined Administration of Streptozotocin and Sucrose Accelerates the Appearance of Type 2 Diabetes Symptoms in Rats

Table 3

Fasting blood glucose (mg/dl) in rats 10 and 14 weeks of age of experimental protocol B. The data shown are of the Control (males , females ), C+10% 7w (males , females ), C+10% 11w (males , females ), C+30% 7w (males , females ), C+30% 11w (males , females ), Stz70 (males , females ), Stz70+10% 7w (males , females ), Stz70+10% 11w (males , females ), Stz70+30% 7w (males , females ), and Stz70+30% 11w (males , females ) groups. Values are expressed as the median and interquartile range (IQR) (p25-p75). Variation between more than two groups was measured by the Kruskal-Wallis test followed by the Dunn Multiple Comparison Test. The asterisk denotes that the data are significantly different from the Control group (, , and ), and the plus sign denotes that the data are significantly different from the Stz70 group (+, ++, and +++).

MaleFemale
10th week14th week10th week14th week

Control97 (91.25-116.8)106.5 (94.5-119.5)93 (92-118)96.5 (89.5-105)
C+10% 7w110 (91-121)111 (98.5-130.5)103 (99-107.5)113 (104.8-118.5)
C+10% 11w110 (99-161)124 (107.3-131.8)105.5 (98-118)109.5 (100.3-114.3)
C+30% 7w99.5 (94.7-108)92.5 (84.7-109)105 (94.5-111)100 (94.2-104.3)
C+30% 11w111.3 (98.7-129.8)104 (94-111.8)117 (98.5-125)115 (94.7-124.5)
Stz70129.5 (120.3-144.8)131 (107-248)131.5 (106.5-153.5)138.5 (113-206)
Stz70+10% 7w125 (99.7-165.3)277 (150.8-361.3)145.5 (138.5151)190 (159.3-223.3)
Stz70+10% 11w137.5 (113-186.3)186.5 (171.8-295.3)125.5 (122-129)172.5 (139-206)
Stz70+30% 7w119.5 (99.7-126.5)157 (136-226.8)138 (116.5155)160.5 (140.8-183.8)
Stz70+30% 11w108 (99-131)154 (120.3-208.5)110 (83-125.5)173.8 (156.8-202.4)