Therapeutic Benefit of Dillenia indica in Diabetes and Its Associated Complications

Table 3

List of studies with Dillenia indica showing beneficial role in diabetes and its associated complications.

S. no.	Part used	Extract used	Phytochemical constituents	Dose	Animal/human study	Treatment	Reference
1.	Leaves	Methanolic extract	Not reported	(250 and 500 mg/kg b.w, p.o.)	Rat	Diabetes	[22]
2.	Leaves	Methanolic extract	Not reported	(250 and 500 mg/kg b.w, p.o.)	Rat	Hyperlipidemia in diabetes	[10]
3.	Leaves	Methanolic extract	Quercetin, β sitosterol, stigmasterol	(10 mg/kg b.w, p.o.)	Rat	Diabetes	[25]
4.	Leaves	Alcoholic extract (DAE)	Flavanoids, terpenoids, chromane	DAE (100, 200, and 400 mg/kg b.w, p.o.) and chromane (5 and 10 mg/kg b.w, p.o.)	Rat	Diabetes	[21]
5.	Leaves	Alcoholic extract (DAE)	Flavanoids, terpenoids, chromane	DAE (100, 200, and 400 mg/kg b.w, p.o.) and chromane(5 and 10 mg/kg b.w, p.o.)	Rat	Diabetic neuropathy	[24]
6.	Leaves	Alcoholic extract (DAE)	Terpenoids-betulinic acid	(100, 200, and 400 mg/kg b.w, p.o.)	Rat	Diabetic nephropathy	[23]
7.	Fruit	Aqueous and methanolic extract	Alkaloids, flavonoids, glycosides, tannins, terpenes, and saponins	(150–550 mg/kg b.w. p.o.)	Mice	Antihyperglycemic and antioxidant activity	[45]
8.	Fruit	Dried fruit powder	Tannins and reducing sugar	30 g/day	Human	Hypoglycemic activity	[35]