Hyperinsulinemia Can Cause Kidney Disease in the IGT Stage of OLETF Rats via the INS/IRS-1/PI3-K/Akt Signaling Pathway

Table 1

Alteration of biochemical markers in different stages of type 2 DM.

Group	FBG (mmol/L)	FINS (uIU/L)	FFA (mmol/L)	TG (mmol/L)	TC (mmol/L)	Weight (g)
Control
NGT
IGT		^ab	^ab	^ab	^ab	^ab
DM	^abc	^abc	^ab	^ab	^ab	^ab
DKD	^abc	^abcd	^ab	^abc	^abcd	^ab
	0.003	0.001	0.014	0.001	0.001	0.001

^a vs. the control group. ^b vs. NGT. ^c vs. IGT. ^d vs. DM.