Effects of High-Fat Diet on eHSP72 and Extra-to-Intracellular HSP70 Levels in Mice Submitted to Exercise under Exposure to Fine Particulate Matter

Table 1

Effects of exercise under PM_2.5 exposure on lung oxidative stress, iHSP70 levels, and eHSP70/iHSP70 ratio levels of HFD-treated mice.

	Rest			Moderate-intensity exercise			High-intensity exercise
	Control	HFD	t-test	Control	HFD	t-test	Control	HFD	t-test
TBARS	0.18 ± 0.06	0.13 ± 0.03		0.32 ± 0.10	0.14 ± 0.02	^∗	0.17 ± 0.02	0.14 ± 0.04
SOD	0.17 ± 0.01	0.19 ± 0.02		0.19 ± 0.02	0.19 ± 0.02		0.20 ± 0.02	0.19 ± 0.03
iHSP70	1.02 ± 0.02	1.27 ± 0.14		1.26 ± 0.27	1.29 ± 0.14		1.08 ± 0.09	1.36 ± 0.24
eHSP70/iHSP70 ratio	1.00 ± 0.31	0.65 ± 0.32		0.94 ± 0.76	0.67 ± 0.39		1.40 ± 0.47	0.42 ± 0.09
	Rest + PM2.5			Moderate Intensity Exercise + PM2.5			High-Intensity Exercise + PM2.5
	Control	HFD	t-test	Control	HFD	t-test	Control	HFD	t-test
TBARS	0.33 ± 0.14	0.13 ± 0.02		0.29 ± 0.07	0.12 ± 0.02		0.14 ± 0.02	0.16 ± 0.06
SOD	0.20 ± 0.01	0.19 ± 0.03		0.17 ± 0.02	0.19 ± 0.04		0.17 ± 0.02	0.18 ± 0.03
iHSP70	1.15 ± 0.05	1.45 ± 0.26		1.30 ± 0.32	1.48 ± 0.19		1.27 ± 0.12	1.20 ± 0.17
eHSP70/iHSP70 ratio	0.76 ± 0.28	0.36 ± 0.09		0.33 ± 0.18	0.65 ± 0.33		0.52 ± 0.06	0.81 ± 0.22