Effects of Genetic Variants of Nuclear Receptor Y on the Risk of Type 2 Diabetes Mellitus

Table 1

Distributions of the NF-YA SNP in T2DM patients and controls.

SNP	Group	Genotype		HWE	Allele
		Number	value	value	Freq. (%)		value	OR [95% CI]
rs2268188		TT/TG/GG			T	G
	T2DM	191/182/54	0.013	0.304	66.0	34.0	0.011	1.31 [1.06–1.61]
	Control	214/158/36		0.380	71.8	28.2
rs6918969		TT/TC/CC			T	C
	T2DM	144/208/75	0.005	0.994	58.1	41.9	0.004	1.34 [1.11–1.63]
	Control	179/172/57		0.136	64.9	35.1
rs28869187		AA/AC/CC			A	C
	T2DM	182/184/61	0.008	0.193	64.2	35.8	0.006	1.33 [1.08–1.64]
	Control	208/159/41		0.198	70.5	29.5
rs35105472		CC/CG/GG			C	G
	T2DM	218/170/39	0.084	0.482	71.0	29.0	0.081	1.21 [0.97–1.54]
	Control	227/156/25		0.793	74.8	25.2
rs76109475		GG/GA/AA			G	A
	T2DM	195/181/51	0.624	0.369	66.9	33.1	0.615	1.05 [0.86–1.29]
	Control	194/167/47		0.231	68.0	32.0

HWE: Hardy-Weinberg equilibrium; OR: odds ratio; CI: confidence interval. P values less than 0.05 are in bold.