In Silico Analysis of Coding/Noncoding SNPs of Human RETN Gene and Characterization of Their Impact on Resistin Stability and Structure

Figure 2

(a) Superimposed of native structure of human resistin (cyan color) onto mutant C51Y structure (white color) showing a deviation RMSD of 1.137 Å. (b) Superimposed of native structure of human resistin (cyan color) onto mutant C104Y structure (white color) showing a deviation RMSD of 1.308 Å. (c) Disulfide bond breakage in C51Y resistin mutant. (d) Disulfide bond between both cysteine residues 51 and 104 in wild-type resistin. (e) Disulfide bond breakage in C104Y resistin mutant.

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