Research Article

Retrospective Analysis of Bone Metabolism in Patients on Waiting List for Simultaneous Pancreas-Kidney Transplantation

Table 1

Anthropometric and laboratory characteristics for the whole group, men, and women, along with gender comparisons.

Total ()Men ()Women ()Significance

Age (yr)40 [32.5 to 49]44 [34 to 51]36.5 [30 to 47]
Diabetes duration (yr)23 [18 to 30]24 [18 to 31]23 [18 to 29]NS
Age of diabetes onset (yr)13 [9.5 to 22]14 [10 to 25]12.5 [9 to 16.3]
BMI (kg/m2)24.2 [22.3 to 27.4]25.0 [23 to 28.1]23.0 [21.1 to 26.7]
HbA1c (mmol/mol) (IFCC)69 [63 to 82]69 [62 to 82]69.5 [63 to 81]NS
 (%) (DCCT)8.46 [7.92 to 9.65]8.46 [7.82 to 9.65]8.51 [7.92 to 9.56]
Daily insulin doses (IU)39 [31 to 49]41 [32 to 51]34 [30 to 44]
GF (mL/min/1.73 m2)13.2 [8.4 to 19.8]15.6 [9.6 to 20.4]11.4 [7.8 to 18.0]
CKD G4 (number)72 (40.7%)54 (47%)18 (29%)
 GF (mL/min/1.73 m2)21.0 [18.0 to 25.8]21.6 [17.4 to 27.0]21.0 [18.6 to 24.0]NS
CKD G5 (number)40 (22.6%)13 (11.3%)27 (43.5%)
 GF (mL/min/1.73 m2)9.6 [7.8 to 13.2]9.6 [8.4 to 13.2]9.6 [7.8 to 12.6]NS
CKD G5D (number)65 (36.7%)48 (41.7%)17 (27.4%)
 GF (mL/min/1.73 m2)8.4 [7.2 to 12.6]10.2 [6.6 to 13.2]7.8 [6.6 to 9.6]NS
s-Ca (mmol/L) ()2.39 [2.31 to 2.46]2.4 [2.3 to 2.45]2.38 [2.33 to 2.48]NS
s-P (mmol/L) ()1.58 [1.38 to 1.85]1.54 [1.36 to 1.77]1.62 [1.41 to 1.9]NS
Alb (g/L)32.9 [29.3 to 37.4]34.4 [30.7 to 38.3]30.6 [26.5 to 35.3]
ALP (ukat/L)1.48 [1.21 to 1.92]1.58 [1.23 to 2.03]1.37 [1.15 to 1.78]NS
PTH (pmol/L) ()15.3 [9.58 to 25.91]15.1 [9.3 to 25.4]15.9 [10.0 to 27.4]NS
25OHD (ng/mL) ()12.7 [10.4 to 19.5]12.8 [10.4 to 20.1]12.3 [10.3 to 18.0]NS
1,25(OH)2D3 (ng/L) ()14.9 [9.9 to 25.7]
(+ 27 undetectable)
14.7 [10.1 to 25.8]
(+ 15 undetectable)
15.2 [9.6 to 23.1]
(+ 12 undetectable)
NS

Data are medians [interquartile ranges].