Expression Profiling and Clinical Significance of Plasma MicroRNAs in Diabetic Nephropathy

Table 3

Diagnostic value of plasma miRNAs for DN.

	Sensitivity (%)	Specificity (%)	AUC	95% CI
Prediction of DN from DM
miR-150-5p	45.5	86.1	0.70	0.576–0.849
miR-155-5p	46.3	93.9	0.71	0.632–0.859
miR-30e	59.4	86.1	0.75	0.582–0.882
miR-3196	71.1	70.6	0.72	0.597–0.836
miR-320e	52.9	91.7	0.64	0.501–0.782
let-7a-5p	50.0	94.4	0.72	0.588–0.846
Prediction of DN from NC
miR-150-5p	100	83.3	0.96	0.603–0.853
miR-155-5p	56.7	78.8	0.73	0.603–0.853
miR-30e	85.0	94.4	0.94	0.878–0.995
miR-3196	84.6	77.1	0.80	0.698–0.897
miR-320e	87.9	91.6	0.93	0.875–0.993
let-7a-5p	87.9	91.7	0.74	0.619–0.869

DN: diabetic nephropathy; NC: normal controls; DM: diabetes mellitus with normoalbuminuria.