Association between Duration of Exercise (MET Hours per Week) and the Risk of Decreased eGFR: A Cross-Sectional Study Based on a Large Chinese Population
Table 4
Correlation analysis between physical activity (MET hours per week) and the risk of decreased eGFR in subgroups.
Variable
Nonadjusted
trend
Model I
trend
Model II
trend
Male
eGFR category
Physical activity (MET hours per week)
0.2692
0.0310
0.0035
<7.5
1.0
1.0
1.0
7.5 to <21
1.27 (1.12, 1.44)
1.05 (0.90, 1.23)
1.05 (0.89, 1.25)
≥21
1.10 (1.00, 1.20)
1.13 (1.01, 1.26)
1.18 (1.05, 1.34)
Continuous eGFR (mL/min/1.73 m2)
Physical activity (MET hours per week)
0.1464
0.8981
0.1057
<7.5
0
0
0
7.5 to <21
-1.95 (-2.95, -0.96)
-0.18 (-0.94, 0.59)
-0.16 (-0.92, 0.60)
≥21
0.08 (-0.63, 0.80)
-0.00 (-0.56, 0.55)
-0.43 (-0.98, 0.13)
Female
eGFR category
Physical activity (MET hours per week)
0.5679
<0.0001
0.0001
<7.5
1.0
1.0
1.0
7.5 to <21
1.19 (1.04, 1.37)
1.25 (1.05, 1.48)
1.25 (1.04, 1.49)
≥21
1.01 (0.91, 1.12)
1.34 (1.17, 1.52)
1.33 (1.15, 1.52)
Continuous eGFR (mL/min/1.73 m2)
Physical activity (MET hours per week)
0.0143
0.0001
<0.0001
<7.5
0
0
0
7.5 to <21
-1.16 (-1.68, -0.64)
-0.74 (-1.21, -0.26)
-0.53 (-1.00, -0.07)
≥21
-0.63 (-1.01, -0.25)
-0.74 (-1.08, -0.39)
-0.75 (-1.09, -0.41)
years
eGFR category
Physical activity (MET hours per week)
0.0351
0.0549
0.2080
<7.5
1.0
1.0
1.0
7.5 to <21
1.19 (0.89, 1.60)
1.11 (0.82, 1.50)
1.16 (0.82, 1.64)
≥21
1.26 (1.02, 1.57)
1.23 (0.99, 1.53)
1.20 (0.93, 1.55)
Continuous eGFR (mL/min/1.73 m2)
Physical activity (MET hours per week)
0.0172
0.1714
0.0031
<7.5
0
0
0
7.5 to <21
-0.94 (-1.39, -0.49)
-0.37 (-0.77, 0.03)
-0.53 (-0.84, -0.22)
≥21
-0.50 (-0.82, -0.19)
-0.24 (-0.52, 0.04)
-0.30 (-0.52, -0.08)
Age 55-64 years
eGFR category
Physical activity (MET hours per week)
<0.0001
<0.0001
<0.0001
<7.5
1.0
1.0
1.0
7.5 to <21
1.05 (0.92, 1.21)
1.04 (0.90, 1.20)
1.09 (0.91, 1.31)
≥21
1.22 (1.11, 1.35)
1.24 (1.12, 1.38)
1.26 (1.10, 1.45)
Continuous eGFR (mL/min/1.73 m2)
Physical activity (MET hours per week)
<0.0001
<0.0001
<0.0001
<7.5
0
0
0
7.5 to <21
-0.69 (-1.35, -0.02)
-0.71 (-1.36, -0.06)
-0.70 (-1.28, -0.12)
≥21
-1.22 (-1.71, -0.73)
-1.22 (-1.71, -0.74)
-1.06 (-1.49, -0.63)
years
eGFR category
Physical activity (MET hours per week)
0.7888
0.2445
0.7046
<7.5
1.0
1.0
1.0
7.5 to <21
1.11 (0.96, 1.28)
1.18 (1.01, 1.37)
1.15 (0.95, 1.38)
≥21
1.05 (0.94, 1.17)
1.23 (1.10, 1.38)
1.15 (1.00, 1.32)
Continuous eGFR (mL/min/1.73 m2)
Physical activity (MET hours per week)
0.6376
0.7733
0.9339
<7.5
0
0
0
7.5 to <21
-0.52 (-2.24, 1.20)
-1.15 (-2.80, 0.50)
-0.31 (-1.73, 1.11)
≥21
-0.51 (-1.81, 0.78)
-2.43 (-3.69, -1.17)
-1.22 (-2.32, -0.13)
Nondiabetes
eGFR category
Physical activity (MET hours per week)
0.0001
<0.0001
<0.0001
<7.5
1.0
1.0
1.0
7.5 to <21
1.23 (1.09, 1.39)
1.13 (0.98, 1.30)
1.18 (0.99, 1.41)
≥21
1.21 (1.11, 1.32)
1.39 (1.25, 1.55)
1.42 (1.24, 1.62)
Continuous eGFR (mL/min/1.73 m2)
Physical activity (MET hours per week)
0.0001
<0.0001
<0.0001
<7.5
0
0
0
7.5 to <21
-1.48 (-2.11, -0.85)
-0.51 (-1.04, 0.02)
-0.38 (-0.85, 0.09)
≥21
-1.06 (-1.52, -0.60)
-1.07 (-1.46, -0.68)
-0.78 (-1.12, -0.44)
Prediabetes
eGFR category
Physical activity (MET hours per week)
0.8518
0.0113
0.9813
<7.5
1.0
1.0
1.0
7.5 to <21
1.21 (1.05, 1.39)
1.17 (0.99, 1.38)
1.22 (0.71, 2.08)
≥21
1.05 (0.94, 1.17)
1.19 (1.05, 1.35)
1.07 (0.71, 1.62)
Continuous eGFR (mL/min/1.73 m2)
Physical activity (MET hours per week)
0.0720
0.0025
0.2905
<7.5
0
0
0
7.5 to <21
-1.69 (-2.70, -0.68)
-0.97 (-1.89, -0.05)
-1.70 (-3.46, 0.06)
≥21
-0.94 (-1.69, -0.19)
-1.11 (-1.79, -0.43)
-0.80 (-2.12, 0.51)
Diabetes
eGFR category
Physical activity (MET hours per week)
0.7555
0.1762
0.7344
<7.5
1.0
1.0
1.0
7.5 to <21
1.05 (0.86, 1.30)
1.03 (0.92, 1.16)
1.21 (0.94, 1.56)
≥21
1.03 (0.89, 1.19)
1.07 (0.96, 1.19)
1.22 (1.00, 1.48)
Continuous eGFR (mL/min/1.73 m2)
Physical activity (MET hours per week)
0.5247
0.8804
0.4650
<7.5
0
0
0
7.5 to <21
-0.53 (-2.21, 1.15)
-0.14 (-1.69, 1.41)
0.12 (-1.26, 1.50)
≥21
0.26 (-0.93, 1.44)
0.05 (-1.05, 1.15)
0.33 (-0.65, 1.31)
Nonadjusted model for none. Model I adjusted for age and BMI. Model II adjusted for age, sex, BMI, region, education level, SBP, DBP, pulse, LDL, HDL, TG, FBG, PBG, HbA1c, GGT, smoking status, drinking status, history of hypertension, cardiovascular history, diabetes history, medication history, and family history of diabetes and tumor.
