| | Variables | Adjusted mean difference (95% CI) of EQ-5D-3L index score | value | Adjusted mean difference (95% CI) of EQ-5D-3L VAS score | value |
| | Hypoglycemia | | None | Reference | <0.001† | Reference | 0.013† | | Mild | -0.156 (-0.225, -0.087) | | -2.92 (-5.61, -0.23) | | | Moderate | -0.096 (-0.183, -0.008) | | -3.17 (-6.59, -0.25) | | | Severe/very severe | -0.198 (-0.373, -0.023) | | -7.89 (-14.71, -1.07) | | | years | -0.057 (-0.118, 0.003) | 0.064 | -0.32 (-2.63, 1.99) | 0.784 | | Male | 0.108 (0.054, 0.161) | <0.001† | 1.48 (-0.57, 3.53) | 0.156 | | Vascular complication | -0.020 (-0.046, 0.087) | 0.547 | -2.24 (-4.77, 0.29) | 0.082 | | Treatment | | SU alone | Reference | 0.049† | Reference | 0.127 | | SU+MET | -0.067 (-0.133, 0.000) | | 1.97 (-0.56, 4.51) | | | Weight change | | None | Reference | 0.003† | Reference | 0.809 | | Gain | -0.116 (-0.189, -0.042) | | 0.83 (-2.05, 3.71) | | | Loss | -0.119 (-0.190, -0.048) | | 0.88 (-1.92, 3.67) | | | Adherence to medication | -0.018 (-0.071, 0.034) | 0.490 | -0.45 (-2.49, 1.60) | 0.668 | | Worry about hypoglycemia/unit score (0 to 4) | -0.059 (-0.103, -0.015) | 0.009† | -3.14 (-4.83, -1.46) | <0.001† | | Fear of weight gain/unit score (0 to 4) | -0.070 (-0.099, -0.041) | <0.001† | -0.73 (-1.85, 0.39) | 0.203 | | Overall satisfaction/unit score (0 to 100) | 0.0016 (-0.0008, 0.0039) | 0.184 | 0.103 (0.014, 0.193) | 0.024† |
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