Research Article
FOXO1 Mediates Advanced Glycation End Products Induced Mouse Osteocyte-Like MLO-Y4 Cell Apoptosis and Dysfunctions
Figure 2
AGE enhances the expression of proapoptotic genes and proteins in MLO-Y4 cells. The mRNA expression of proapoptotic genes p53 and Bax was measured via qPCR. (a) Quantifications of p53-relative mRNA expression. (b) Quantifications of Bax-relative mRNA expression. Western blot was performed to detect p53, Bax, and cleaved caspase-3 expression in protein level. (c) Western blot representative images. (d) Quantifications of cleaved caspase-3-relative expression. (e) Quantifications of p53-relative expression. (f) Quantifications of Bax-relative expression. All error bars are standard deviation of the mean. compared to the BSA control group.
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