Serum Carnosinase-1 and Albuminuria Rather than the CNDP1 Genotype Correlate with Urinary Carnosinase-1 in Diabetic and Nondiabetic Patients with Chronic Kidney Disease

Figure 1

(a) Distribution of CN-1 in spot urine of T2DM and nondiabetic patients (CKD) with normo- or microalbuminuria () and macroalbuminuria (). Results for each individual patient are shown as well as the median and IQR (lines) for each of the different groups. (b) Pearson correlation between ACR [log (ACR)] and urinary CN-1 concentrations [log (urinary CN-1)] in patients with T2DM and nondiabetic CKD patients (). (c) Distribution of urinary CN-1 concentrations in all patients according to eGFR. T2DM and CKD patients () were stratified according to reduced () () and preserved renal function () (). eGFR was estimated using the CKD-EPI formula. Boxes and whiskers represent the median and IQR. Outliers are indicated by circles.

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