Apolipoproteins A and B and PCSK9: Nontraditional Cardiovascular Risk Factors in Chronic Kidney Disease and in End-Stage Renal Disease

Figure 4

The roles of ApoB. In the liver, ApoB promotes the formation of nascent VLDL and also is essential for the linking of LDL particles to LDLR for cellular absorption and degradation of LDL particles. In the intestine, ApoB stimulates the formation of chylomicrons. LDL: low-density lipoprotein; VLDL: very low-density lipoprotein.